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Structural and Functional Basis of a Role for CRKL in a Fibroblast Growth Factor 8-Induced Feed-Forward Loop

The adapter protein CRKL is required for the normal development of multiple tissues that rely on fibroblast growth factor 8 (FGF8). The precise role of CRKL in receptor signaling has been unclear, however. To address this issue, we first modeled the three-dimensional structure of CRKL by molecular d...

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Detalhes bibliográficos
Main Authors: Seo, Ji-Heui, Suenaga, Atsushi, Hatakeyama, Mariko, Taiji, Makoto, Imamoto, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681998/
https://ncbi.nlm.nih.gov/pubmed/19307307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01686-08
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