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vfr, a Novel Locus Affecting Cysteine Protease Production in Streptococcus pyogenes

A gene unique to Streptococcus pyogenes, called vfr, that negatively regulates speB, an important extracellular proteinase, has been identified. Disruption of vfr markedly increased SpeB production in a clinical strain of S. pyogenes and relieved its growth phase dependency. These findings may provi...

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Detalhes bibliográficos
Main Authors: Ma, Yongsheng, Bryant, Amy E., Salmi, Dan B., McIndoo, Eric, Stevens, Dennis L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681797/
https://ncbi.nlm.nih.gov/pubmed/19270089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01771-08
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