Molecular Genetics of para-Aminosalicylic Acid Resistance in Clinical Isolates and Spontaneous Mutants of Mycobacterium tuberculosis

The emergence of Mycobacterium tuberculosis resistant to first-line antibiotics has renewed interest in second-line antitubercular agents. Here, we aimed to extend our understanding of the mechanisms underlying para-aminosalicylic acid (PAS) resistance by analysis of six genes of the folate metaboli...

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Detalhes bibliográficos
Main Authors: Mathys, Vanessa, Wintjens, René, Lefevre, Philippe, Bertout, Julie, Singhal, Amit, Kiass, Mehdi, Kurepina, Natalia, Wang, Xiao-Ming, Mathema, Barun, Baulard, Alain, Kreiswirth, Barry N., Bifani, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681553/
https://ncbi.nlm.nih.gov/pubmed/19237648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01197-08
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