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Proteins of the origin recognition complex (ORC) and DNA topoisomerases on mammalian chromatin

BACKGROUND: The process of DNA replication requires the separation of complementary DNA strands. In this process, the unwinding of circularly closed or long DNA duplices leads to torsional tensions which must be released by topoisomerases. So topoisomerases play an important role in DNA replication....

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Detalhes bibliográficos
Main Authors: Hu, Hong-gang, Baack, Martina, Knippers, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681468/
https://ncbi.nlm.nih.gov/pubmed/19397829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-10-36
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