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FGF-1 induces expression of LXRα and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes

Fibroblast growth factor 1 (FGF-1) enhances apolipoprotein E (apoE) expression and apoE-HDL biogenesis in autocrine fashion in astrocytes (Ito, J., Y. Nagayasu, R. Lu, A. Kheirollah, M. Hayashi, and S. Yokoyama. Astrocytes produce and secrete FGF-1, which promotes the production of apoE-HDL in a man...

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Dettagli Bibliografici
Autori principali: Lu, Rui, Ito, Jinichi, Iwamoto, Noriyuki, Nishimaki-Mogami, Tomoko, Yokoyama, Shinji
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681397/
https://ncbi.nlm.nih.gov/pubmed/19229075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800594-JLR200
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