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Regulation of cardiac fibroblast collagen synthesis by adenosine: roles for Epac and PI3K
Rat cardiac fibroblasts (CF) express multiple adenosine (ADO) receptors. Pharmacological evidence suggests that activation of A(2) receptors may inhibit collagen synthesis via adenylyl cyclase-induced elevation of cellular cAMP. We have characterized the signaling pathways involved in ADO-mediated i...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681376/ https://ncbi.nlm.nih.gov/pubmed/19279233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00291.2008 |
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