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SHP-2 IS A NOVEL TARGET OF ABL KINASES DURING CELL PROLIFERATION
Previously, we showed that Abl family tyrosine kinases are activated by growth factors, and c-Abl is required for transition from G1 to S phase during PDGF-mediated proliferation. Here, we show that the SHP-2 tyrosine phosphatase, which acts to promote proliferation in response to cytokines and grow...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681299/ https://ncbi.nlm.nih.gov/pubmed/18827006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.035691 |
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