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Investigation of Cosolute-Protein Preferential Interaction Coefficients: New Insight into the Mechanism by Which Arginine Inhibits Aggregation

The relatively new technique of vapor pressure osmometry was utilized to determine the preferential interaction of five common solution additives (arginine HCl, guanidine HCl, glycerol, glucose, and urea) using three different model proteins (BSA, lysozyme, and α-chymotrypsinogen). Results for guani...

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Autori principali: Schneider, Curtiss P., Trout, Bernhardt L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681293/
https://ncbi.nlm.nih.gov/pubmed/19199688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp808042w
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