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Avicin D: A Protein Reactive Plant Isoprenoid Dephosphorylates Stat 3 by Regulating Both Kinase and Phosphatase Activities

Avicins, a class of electrophilic triterpenoids with pro-apoptotic, anti-inflammatory and antioxidant properties, have been shown to induce redox-dependant post-translational modification of cysteine residues to regulate protein function. Based on (a) the cross-talk that occurs between redox and pho...

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Bibliographic Details
Main Authors: Haridas, Valsala, Nishimura, Goshi, Xu, Zhi-Xiang, Connolly, Fiona, Hanausek, Margaret, Walaszek, Zbigniew, Zoltaszek, Robert, Gutterman, Jordan U.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680980/
https://ncbi.nlm.nih.gov/pubmed/19440292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005578
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