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Homologous desensitization of signalling by the alpha (α) isoform of the human thromboxane A(2) receptor: A specific role for nitric oxide signalling

Thromboxane (TX) A(2) plays a central role in hemostasis, regulating platelet activation status and vascular tone. We have recently established that the TPβ isoform of the human TXA(2) receptor (TP) undergoes rapid, agonist-induced homologous desensitization of signalling largely through a G protein...

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Detalles Bibliográficos
Main Authors: Kelley-Hickie, Leanne P., O'Keeffe, Martina B., Reid, Helen M., Kinsella, B. Therese
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Pub. Co 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680961/
https://ncbi.nlm.nih.gov/pubmed/17466390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2007.03.012
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