A mathematical model of aging-related and cortisol induced hippocampal dysfunction

BACKGROUND: The hippocampus is essential for declarative memory synthesis and is a core pathological substrate for Alzheimer's disease (AD), the most common aging-related dementing disease. Acute increases in plasma cortisol are associated with transient hippocampal inhibition and retrograde am...

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Bibliographic Details
Main Authors: McAuley, Mark T, Kenny, Rose Anne, Kirkwood, Thomas BL, Wilkinson, Darren J, Jones, Janette JL, Miller, Veronica M
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680862/
https://ncbi.nlm.nih.gov/pubmed/19320982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-10-26
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