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Absorption, Distribution, Metabolism, and Excretion of 2,2-Bis(bromomethyl)-1,3-propanediol in Male Fischer-344 Rats

2,2-Bis(bromomethyl)-1,3-propanediol (BMP) is a brominated flame retardant, previously shown to be a multisite carcinogen in experimental animals. Studies were performed to characterize the dispositional and metabolic fate of BMP after oral or intravenous administration to male Fischer-344 rats. Aft...

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Détails bibliographiques
Auteurs principaux: Hoehle, Simone I., Knudsen, Gabriel A., Sanders, J. Michael, Sipes, I. Glenn
Format: Artigo
Langue:Inglês
Publié: American Society for Pharmacology and Experimental Therapeutics 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680524/
https://ncbi.nlm.nih.gov/pubmed/19029203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.023937
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