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Ectopic bone morphogenetic proteins 5 and 4 in the chicken forebrain lead to cyclopia and holoprosencephaly

Proper dorsal–ventral patterning in the developing central nervous system requires signals from both the dorsal and ventral portions of the neural tube. Data from multiple studies have demonstrated that bone morphogenetic proteins (BMPs) and Sonic hedgehog protein are secreted factors that regulate...

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Detalhes bibliográficos
Main Authors: Golden, Jeffrey A., Bracilovic, Ana, McFadden, Kathryn A., Beesley, Jacqueline S., Rubenstein, John L.R., Grinspan, Judith B.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26803/
https://ncbi.nlm.nih.gov/pubmed/10051661
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