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Roles of Bone Morphogenetic Protein signaling and its antagonism in holoprosencephaly

Holoprosencephaly (HPE) is the most common malformation of the forebrain, resulting from a failure to completely septate the left and right hemispheres at the rostral end of the neural tube. Because of the tissue interactions that drive head development, these forebrain defects are typically accompa...

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Autori principali: Klingensmith, John, Matsui, Maiko, Yang, Yu-Ping, Anderson, Ryan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016013/
https://ncbi.nlm.nih.gov/pubmed/20104603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.c.30256
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