Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms

BACKGROUND: The use of methotrexate is limited by interindividual variability in response. Previous studies in patients with either rheumatoid arthritis or psoriasis suggest that genetic variation across the methotrexate metabolic pathway might enable prediction of both efficacy and toxicity of the...

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Bibliographic Details
Main Authors: Warren, RB, Smith, RL, Campalani, E, Eyre, S, Smith, CH, Barker, JNWN, Worthington, J, Griffiths, CEM
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680291/
https://ncbi.nlm.nih.gov/pubmed/19016697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2133.2008.08898.x
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