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Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms

BACKGROUND: The use of methotrexate is limited by interindividual variability in response. Previous studies in patients with either rheumatoid arthritis or psoriasis suggest that genetic variation across the methotrexate metabolic pathway might enable prediction of both efficacy and toxicity of the...

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Detalhes bibliográficos
Main Authors: Warren, RB, Smith, RL, Campalani, E, Eyre, S, Smith, CH, Barker, JNWN, Worthington, J, Griffiths, CEM
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680291/
https://ncbi.nlm.nih.gov/pubmed/19016697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2133.2008.08898.x
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