Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms

BACKGROUND: The use of methotrexate is limited by interindividual variability in response. Previous studies in patients with either rheumatoid arthritis or psoriasis suggest that genetic variation across the methotrexate metabolic pathway might enable prediction of both efficacy and toxicity of the...

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Главные авторы: Warren, RB, Smith, RL, Campalani, E, Eyre, S, Smith, CH, Barker, JNWN, Worthington, J, Griffiths, CEM
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2009
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680291/
https://ncbi.nlm.nih.gov/pubmed/19016697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2133.2008.08898.x
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