Novel Escherichia coli RF1 mutants with decreased translation termination activity and increased sensitivity to the cytotoxic effect of the bacterial toxins Kid and RelE

Novel mutations in prfA, the gene for the polypeptide release factor RF1 of Escherichia coli, were isolated using a positive genetic screen based on the parD (kis, kid) toxin–antitoxin system. This original approach allowed the direct selection of mutants with altered translational termination effic...

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Hlavní autoři: Diago-Navarro, Elizabeth, Mora, Liliana, Buckingham, Richard H, Díaz-Orejas, Ramón, Lemonnier, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2008
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680264/
https://ncbi.nlm.nih.gov/pubmed/19019162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06510.x
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