MYOSIN PHOSPHATASE TARGETING SUBUNIT1 REGULATES MITOSIS BY ANTAGONIZING POLO-LIKE KINASE1

Myosin phosphatase targeting subunit1 (MYPT1) binds to the catalytic subunit of protein phosphatase1 (PP1C). This binding is believed to target PP1C to specific substrates including myosin II, thus controlling cellular contractility. Surprisingly, we found that during mitosis mammalian MYPT1 binds t...

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Main Authors: Yamashiro, S., Yamakita, Y., Totsukawa, G., Goto, H., Kaibuchi, K., Ito, M., Hartshorne, D., Matsumura, F.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680213/
https://ncbi.nlm.nih.gov/pubmed/18477460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.02.013
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