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MYOSIN PHOSPHATASE TARGETING SUBUNIT1 REGULATES MITOSIS BY ANTAGONIZING POLO-LIKE KINASE1
Myosin phosphatase targeting subunit1 (MYPT1) binds to the catalytic subunit of protein phosphatase1 (PP1C). This binding is believed to target PP1C to specific substrates including myosin II, thus controlling cellular contractility. Surprisingly, we found that during mitosis mammalian MYPT1 binds t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680213/ https://ncbi.nlm.nih.gov/pubmed/18477460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.02.013 |
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