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Vitamin D Receptor–Dependent 1α,25(OH)(2) Vitamin D(3)–Induced Anti-Apoptotic PI3K/AKT Signaling in Osteoblasts
Osteoblast apoptosis plays a crucial role in bone remodeling. Physiological doses of 1α,25(OH)(2)-vitamin D(3) (1,25D) protect osteoblasts against apoptosis by means of mechanisms only partially understood. We studied activation of an Akt survival cascade downstream of 1,25D nongenomic stimulation o...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Amer Soc Bone & Mineral Res.
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680173/ https://ncbi.nlm.nih.gov/pubmed/18410228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080326 |
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