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Abnormal differentiation, hyperplasia and embryonic/perinatal lethality in BK5-T/t transgenic mice
The cell-of-origin has a great impact on the types of tumors that develop and the stem/progenitor cells have long been considered main targets of malignant transformation. The SV40 large T and small t antigens (T/t), have been targeted to multiple differentiated cellular compartments in transgenic m...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680132/ https://ncbi.nlm.nih.gov/pubmed/19272531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2008.10.011 |
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