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Pafah1b2 mutations suppress the development of hydrocephalus in compound Pafah1b1;Reln and Pafah1b1;Dab1 mutant mice
Reelin, an extracellular protein that signals through the Dab1 adapter protein, and Lis1 regulate neuronal migration and cellular layer formation in the brain. Loss of Reelin and reduction in Lis1 activity in mice or humans results in the disorganization of cortical structures. Lis1, the product of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680094/ https://ncbi.nlm.nih.gov/pubmed/18514414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.04.096 |
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