The Lysyl Oxidase Inhibitor, β-Aminopropionitrile, Diminishes the Metastatic Colonization Potential of Circulating Breast Cancer Cells

Lysyl oxidase (LOX), an extracellular matrix remodeling enzyme, appears to have a role in promoting breast cancer cell motility and invasiveness. In addition, increased LOX expression has been correlated with decreases in both metastases-free, and overall survival in breast cancer patients. With thi...

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Bibliografiske detaljer
Main Authors: Bondareva, Alla, Downey, Charlene M., Ayres, Fabio, Liu, Wei, Boyd, Steven K., Hallgrimsson, Benedikt, Jirik, Frank R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680032/
https://ncbi.nlm.nih.gov/pubmed/19440335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005620
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