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Abrogation of the Transactivation Activity of p53 by BCCIP Down-regulation
The tumor suppression function of p53 is mostly conferred by its transactivation activity, which is inactivated by p53 mutations in ~50% of human cancers. In cancers harboring wild type p53, the p53 transactivation activity may be compromised by other mechanisms. Identifying the mechanisms by which...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679999/ https://ncbi.nlm.nih.gov/pubmed/17135243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M607520200 |
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