The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
Recently, Salmonella spp. were shown to induce apoptosis in infected macrophages. The mechanism responsible for this process is unknown. In this report, we establish that the Inv-Spa type III secretion apparatus target invasin SipB is necessary and sufficient for the induction of apoptosis. Purified...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1999
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051653/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2396 |
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