Ikaros Stability and Pericentromeric Localization Are Regulated by Protein Phosphatase 1

Ikaros encodes a zinc finger protein that is involved in gene regulation and chromatin remodeling. The majority of Ikaros localizes at pericentromeric heterochromatin (PC-HC) where it regulates expression of target genes. Ikaros function is controlled by posttranslational modification. Phosphorylati...

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Autors principals: Popescu, Marcela, Gurel, Zafer, Ronni, Tapani, Song, Chunhua, Hung, Ka Ying, Payne, Kimberly J., Dovat, Sinisa
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Mechanisms of Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679487/
https://ncbi.nlm.nih.gov/pubmed/19282287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900209200
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