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Recruitment of Ikaros to Pericentromeric Heterochromatin Is Regulated by Phosphorylation
Ikaros encodes a zinc finger protein that is involved in heritable gene silencing. In hematopoietic cells, Ikaros localizes to pericentromeric heterochromatin (PC-HC) where it recruits its target genes, resulting in their activation or repression via chromatin remodeling. The function of Ikaros is c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276389/ https://ncbi.nlm.nih.gov/pubmed/18223295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707906200 |
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