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Recruitment of Ikaros to Pericentromeric Heterochromatin Is Regulated by Phosphorylation

Ikaros encodes a zinc finger protein that is involved in heritable gene silencing. In hematopoietic cells, Ikaros localizes to pericentromeric heterochromatin (PC-HC) where it recruits its target genes, resulting in their activation or repression via chromatin remodeling. The function of Ikaros is c...

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Main Authors: Gurel, Zafer, Ronni, Tapani, Ho, Sam, Kuchar, Jason, Payne, Kimberly J., Turk, Christoph W., Dovat, Sinisa
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276389/
https://ncbi.nlm.nih.gov/pubmed/18223295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707906200
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