A carregar...

Cerebral Cavernous Malformation 2 Protein Promotes Smad Ubiquitin Regulatory Factor 1-mediated RhoA Degradation in Endothelial Cells

Mutation of CCM2 predisposes individuals to cerebral cavernous malformations, vascular abnormalities that cause seizures and hemorrhagic stroke. CCM2 has been proposed to regulate the activity of RhoA for maintenance of vascular integrity. Herein, we define a novel mechanism where the CCM2 phosphoty...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Crose, Lisa E. S., Hilder, Thomas L., Sciaky, Noah, Johnson, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679429/
https://ncbi.nlm.nih.gov/pubmed/19318350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C900009200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!