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Protein Ionizable Groups: pK Values and Their Contribution to Protein Stability and Solubility

The structure, stability, solubility, and function of proteins depend on their net charge and on the ionization state of the individual residues. Consequently, biochemists are interested in the pK values of the ionizable groups in proteins and how these pK values depend on their environment. We revi...

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Bibliografski detalji
Glavni autori: Pace, C. Nick, Grimsley, Gerald R., Scholtz, J. Martin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679426/
https://ncbi.nlm.nih.gov/pubmed/19164280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800080200
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