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Reversing adipocyte differentiation: Implications for treatment of obesity

Conventional treatment of obesity reduces fat in mature adipocytes but leaves them with lipogenic enzymes capable of rapid resynthesis of fat, a likely factor in treatment failure. Adenovirus-induced hyperleptinemia in normal rats results in rapid nonketotic fat loss that persists after hyperleptine...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zhou, Yan-Ting, Wang, Zhuo-Wei, Higa, Moritake, Newgard, Christopher B., Unger, Roger H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26794/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2391
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