Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cells

We previously reported that trichostatin A (TSA), a histone deacetylase (HDAC) inhibitor, induced DLC-1 mRNA expression and accumulated acetylated histones H3 and H4 associated with the DLC-1 promoter in DLC-1 non-expressing gastric cancer cells. In this study, we demonstrated the molecular mechanis...

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Detalhes bibliográficos
Main Authors: Kim, Tai Young, Kim, In Sook, Jong, Hyun-Soon, Lee, Jung Weon, Kim, Tae-You, Jung, Mira, Bang, Yung-Jue
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Medical Biochemistry and Molecular Biology 2008
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679347/
https://ncbi.nlm.nih.gov/pubmed/19116449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2008.40.6.639
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