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Inhibition of advanced glycation endproduct formation by acetaldehyde: Role in the cardioprotective effect of ethanol

Epidemiological studies suggest that there is a beneficial effect of moderate ethanol consumption on the incidence of cardiovascular disease. Ethanol is metabolized to acetaldehyde, a two-carbon carbonyl compound that can react with nucleophiles to form covalent addition products. We have identified...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Al-Abed, Yousef, Mitsuhashi, Tomoko, Li, Hongwei, Lawson, John A., FitzGerald, Garret A., Founds, Hank, Donnelly, Thomas, Cerami, Anthony, Ulrich, Peter, Bucala, Richard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2385
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