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Structure-antimicrobial activity relationship between pleurocidin and its enantiomer

To develop novel antibiotic peptides useful as therapeutic drugs, the enantiomeric analogue of pleurocidin (Ple), which is a well known 25-mer antimicrobial peptide, was designed for proteolytic resistance by D-amino acids substitution. The proteolytic resistance was confirmed by using HPLC after th...

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מידע ביבליוגרפי
Main Authors: Lee, Juneyoung, Lee, Dong Gun
פורמט: Artigo
שפה:Inglês
יצא לאור: Korean Society of Medical Biochemistry and Molecular Biology 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679270/
https://ncbi.nlm.nih.gov/pubmed/18779649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2008.40.4.370
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