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Structure-antimicrobial activity relationship between pleurocidin and its enantiomer
To develop novel antibiotic peptides useful as therapeutic drugs, the enantiomeric analogue of pleurocidin (Ple), which is a well known 25-mer antimicrobial peptide, was designed for proteolytic resistance by D-amino acids substitution. The proteolytic resistance was confirmed by using HPLC after th...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Korean Society of Medical Biochemistry and Molecular Biology
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679270/ https://ncbi.nlm.nih.gov/pubmed/18779649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2008.40.4.370 |
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