Prospective Identification of Malaria Parasite Genes under Balancing Selection

BACKGROUND: Endemic human pathogens are subject to strong immune selection, and interrogation of pathogen genome variation for signatures of balancing selection can identify important target antigens. Several major antigen genes in the malaria parasite Plasmodium falciparum have shown such signature...

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Detalhes bibliográficos
Main Authors: Tetteh, Kevin K. A., Stewart, Lindsay B., Ochola, Lynette Isabella, Amambua-Ngwa, Alfred, Thomas, Alan W., Marsh, Kevin, Weedall, Gareth D., Conway, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679211/
https://ncbi.nlm.nih.gov/pubmed/19440377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005568
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