Population Genomic Scan for Candidate Signatures of Balancing Selection to Guide Antigen Characterization in Malaria Parasites

Acquired immunity in vertebrates maintains polymorphisms in endemic pathogens, leading to identifiable signatures of balancing selection. To comprehensively survey for genes under such selection in the human malaria parasite Plasmodium falciparum, we generated paired-end short-read sequences of para...

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Detalhes bibliográficos
Main Authors: Amambua-Ngwa, Alfred, Tetteh, Kevin K. A., Manske, Magnus, Gomez-Escobar, Natalia, Stewart, Lindsay B., Deerhake, M. Elizabeth, Cheeseman, Ian H., Newbold, Christopher I., Holder, Anthony A., Knuepfer, Ellen, Janha, Omar, Jallow, Muminatou, Campino, Susana, MacInnis, Bronwyn, Kwiatkowski, Dominic P., Conway, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486833/
https://ncbi.nlm.nih.gov/pubmed/23133397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002992
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