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Adaptive Variation Regulates the Expression of the Human SGK1 Gene in Response to Stress

The Serum and Glucocorticoid-regulated Kinase1 (SGK1) gene is a target of the glucocorticoid receptor (GR) and is central to the stress response in many human tissues. Because environmental stress varies across habitats, we hypothesized that natural selection shaped the geographic distribution of ge...

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Detalhes bibliográficos
Main Authors: Luca, Francesca, Kashyap, Sonal, Southard, Catherine, Zou, Min, Witonsky, David, Di Rienzo, Anna, Conzen, Suzanne D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679193/
https://ncbi.nlm.nih.gov/pubmed/19461886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000489
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