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Adaptive Variation Regulates the Expression of the Human SGK1 Gene in Response to Stress

The Serum and Glucocorticoid-regulated Kinase1 (SGK1) gene is a target of the glucocorticoid receptor (GR) and is central to the stress response in many human tissues. Because environmental stress varies across habitats, we hypothesized that natural selection shaped the geographic distribution of ge...

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Sonraí Bibleagrafaíochta
Main Authors: Luca, Francesca, Kashyap, Sonal, Southard, Catherine, Zou, Min, Witonsky, David, Di Rienzo, Anna, Conzen, Suzanne D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679193/
https://ncbi.nlm.nih.gov/pubmed/19461886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000489
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