Integrins mediate adhesion of medulloblastoma cells to tenascin and activate pathways associated with survival and proliferation

Medulloblastoma spreads by leptomeningeal dissemination rather than by infiltration that characterizes other CNS tumors, eg, gliomas. This study represents an initial attempt to identify both the molecules that mediate medulloblastoma adhesion to leptomeninges and the pathways that are key to surviv...

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Detalhes bibliográficos
Main Authors: Fiorilli, Paul, Partridge, Darren, Staniszewska, Izabela, Wang, Jin Y, Grabacka, Maja, So, Kelvin, Marcinkiewicz, Cezary, Reiss, Krzysztof, Khalili, Kamel, Croul, Sidney E
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679155/
https://ncbi.nlm.nih.gov/pubmed/18794852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2008.89
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