Manipulation of Cell:Cell Contacts and Mesoderm Suppressing Activity Direct Lineage Choice from Pluripotent Primitive Ectoderm-Like Cells in Culture

In the mammal, the pluripotent cells of embryo differentiate and commit to either the mesoderm/endoderm lineages or the ectoderm lineage during gastrulation. In culture, the ability to direct lineage choice from pluripotent cells into the mesoderm/endoderm or ectoderm lineages will enable the develo...

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Detalhes bibliográficos
Main Authors: Hughes, James N., Washington, Jennifer M., Zheng, Zhiqiang, Lau, Xiuwen K., Yap, Charlotte, Rathjen, Peter D., Rathjen, Joy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679147/
https://ncbi.nlm.nih.gov/pubmed/19440553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005579
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