Major Trypanosoma cruzi antigenic determinant in Chagas' heart disease shares homology with the systemic lupus erythematosus ribosomal P protein epitope.

A Trypanosoma cruzi lambda gt11 cDNA clone, JL5, expressed a recombinant protein which was found to react predominantly with chronic Chagas' heart disease sera. The cloned 35-residue-long peptide was identified as the carboxyl-terminal portion of a T. cruzi ribosomal P protein. The JL5 13 carbo...

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Publicat a:J Clin Microbiol
Autors principals: Mesri, E A, Levitus, G, Hontebeyrie-Joskowicz, M, Dighiero, G, Van Regenmortel, M H, Levin, M J
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1990
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC267908/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1696282/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.28.6.1219-1224.1990
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