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NF-κB AND ZBP-89 REGULATE MMP-3 EXPRESSION VIA A POLYMORPHIC SITE IN THE PROMOTER
A 5T/6T polymorphism in the human MMP-3 promoter affects gene expression and impacts the risk and/or severity of various pathological conditions. Chromatin immunoprecipitation (ChIP) in human fibroblasts homozygous for the 6T site demonstrate that it is bound by NF-κB and ZBP-89 transcription factor...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678966/ https://ncbi.nlm.nih.gov/pubmed/19275880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.03.002 |
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