Interleukin-4 inhibition of interleukin-1-induced expression of matrix metalloproteinase-3 (MMP-3) is independent of lipoxygenase and PPARγ activation in human gingival fibroblasts

BACKGROUND: Interleukin 4 (IL-4) has been shown to suppress interleukin-1 (IL-1) induced expression of matrix metalloproteinase-3 (MMP-3) in human synovial and gingival fibroblasts, but the mechanism of suppression has not been determined. Activators of peroxisome proliferator-activated receptor-γ (...

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Main Authors: Stewart, Denise, Javadi, Masoud, Chambers, Mariah, Gunsolly, Chad, Gorski, Grzegorz, Borghaei, Ruth C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810308/
https://ncbi.nlm.nih.gov/pubmed/17319946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-12
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