載入...
Approaches to Handling Data When a Phase II Trial Deviates from the Pre-specified Simon's Two-Stage Design
Simon's ‘optimal’ and ‘minimax’ two-stage designs are common methods for conducting phase IIA studies investigating new cancer therapies. However, these designs are rather rigid in their settings because of the pre-specified rejection rules and fixed sample sizes at each stage. In practice, we...
Na minha lista:
| Main Authors: | , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678911/ https://ncbi.nlm.nih.gov/pubmed/18800338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3426 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|