The p53-induced Siva-1 plays a significant role in cisplatin-mediated apoptosis

BACKGROUND: The pro-apoptotic protein Siva-1 functions in both extrinsic and intrinsic cell death signaling; however, the exact contribution of the endogenous Siva-1 to DNA damage-induced apoptosis is unclear. Using cisplatin, a chemotherapeutic drug, to induce DNA damage and cell death, we determin...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Barkinge, John L., Gudi, Radhika, Sarah, Hawkins, Chu, Fei, Borthakur, Alip, Prabhakar, Bellur S., Prasad, Kanteti V.S.
Format: Artigo
Langue:Inglês
Publié: Medknow Publications 2009
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678867/
https://ncbi.nlm.nih.gov/pubmed/19240372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.45389
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