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BKV and JCV large T antigen-specific CD8(+) T cell response in HLA A*0201(+) kidney transplant recipients with polyomavirus nephropathy and patients with progressive multifocal leukoencephalopathy
BACKGROUND: BK virus (BKV), which causes polyomavirus-associated nephropathy (PVN) in kidney transplant recipients (KTx), has 75% homology with JC virus (JCV), the etiologic agent of progressive multifocal leukoencephalopathy (PML). The large T-antigen (T-ag) is the main regulatory protein of polyom...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678795/ https://ncbi.nlm.nih.gov/pubmed/18295538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcv.2008.01.005 |
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