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WIP is critical for T cell responsiveness to IL-2

The Wiskott-Aldrich syndrome (WAS) interacting protein (WIP) stabilizes the WAS protein (WASP), the product of the gene mutated in WAS. WIP-deficient T cells have low WASP levels, limiting the usefulness of WIP KO mice in defining the role of WIP in T cell function. To define this role, we compared...

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Hlavní autoři: Le Bras, Severine, Massaad, Michel, Koduru, Suresh, Kumar, Lalit, Oyoshi, Michiko K., Hartwig, John, Geha, Raif S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678629/
https://ncbi.nlm.nih.gov/pubmed/19359486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806410106
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