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Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants
The structural and dynamical properties of the metal-free form of WT human superoxide dismutase 1 (SOD1) and its familial amyotrophic lateral sclerosis (fALS)-related mutants, T54R and I113T, were characterized both in solution, through NMR, and in the crystal, through X-ray diffraction. We found th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678485/ https://ncbi.nlm.nih.gov/pubmed/19369197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809845106 |
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