Dominant Negative Mutants of Bacillus thuringiensis Cry1Ab Toxin Function as Anti-Toxins: Demonstration of the Role of Oligomerization in Toxicity

BACKGROUND: Bacillus thuringiensis Cry toxins, that are used worldwide in insect control, kill insects by a mechanism that depends on their ability to form oligomeric pores that insert into the insect-midgut cells. These toxins are being used worldwide in transgenic plants or spray to control insect...

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Autori principali: Rodríguez-Almazán, Claudia, Zavala, Luis Enrique, Muñoz-Garay, Carlos, Jiménez-Juárez, Nuria, Pacheco, Sabino, Masson, Luke, Soberón, Mario, Bravo, Alejandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678262/
https://ncbi.nlm.nih.gov/pubmed/19440244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005545
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