Dominant Negative Phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba Mutants Suggest Hetero-Oligomer Formation among Different Cry Toxins

BACKGROUND: Bacillus thuringiensis Cry toxins are used worldwide in the control of different insect pests important in agriculture or in human health. The Cry proteins are pore-forming toxins that affect the midgut cell of target insects. It was shown that non-toxic Cry1Ab helix α-4 mutants had a do...

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Auteurs principaux: Carmona, Daniela, Rodríguez-Almazán, Claudia, Muñoz-Garay, Carlos, Portugal, Leivi, Pérez, Claudia, de Maagd, Ruud A., Bakker, Petra, Soberón, Mario, Bravo, Alejandra
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095643/
https://ncbi.nlm.nih.gov/pubmed/21603577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019952
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